carbamazepine will lower the level or influence of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
modafinil will improve the amount or impact of pantoprazole by influencing hepatic enzyme CYP2C19 metabolism. Slight/Significance Unidentified. Net impact on pantoprazole actions not known as a result of opposing effects of CYP450 enzymes; keep track of
In vitro measurements indicate that sixty% of modafinil is sure to plasma proteins at clinical concentrations with the drug. This percentage adjustments hardly any when the focus of modafinil is assorted.[146]
tecovirimat will raise the level or outcome of modafinil by impacting hepatic enzyme CYP2C19 metabolism. Use Caution/Check. Tecovirimat can be a weak inhibitor of CYP2C8 and CYP2C19. Observe for adverse consequences if coadministered with sensitive substrates of those enzymes.
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Shantia shares facts regarding the dialogue she and her doctor had about starting FYCOMPA to take care of her seizures.
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crizotinib increases amounts of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Dose reduction may very well be required for coadministered medications which have been predominantly metabolized by CYP3A.
cenobamate will improve the degree or result of modafinil by impacting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Check Carefully. Take into account modafinil dosage a dose reduction of CYP2C19 substrates, as clinically proper, when utilized concomitantly with cenobamate.
If excessive is taken, it may well become behavior-forming. This medication includes a Medication Guide. It is essential you examine and understand this details. Be sure you question your health care provider about something you do not realize.
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No particular antidote exists to the poisonous outcomes of the PROVIGIL overdose. This kind of overdoses needs to be managed with principally supportive treatment, together with cardiovascular checking.
The equal armodafinil dose to That is one hundred fifty mg, that's the dosage supplied within the generic variations Artvigil and Modvigil.
It isn't regarded regardless of whether modafinil passes into breast milk or if it could hurt a nursing baby. Explain to your health care provider If you're breast-feeding a infant.